Standardization of the first Korean national reference standard for snake (Gloydius brevicaudus) antivenom
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چکیده
منابع مشابه
Standardization of regional reference for mamushi (Gloydius blomhoffii) antivenom in Japan, Korea, and China.
The mamushi (Gloydius blomhoffii) snakes that inhabit Japan, Korea, and China produce venoms with similar serological characters to each other. Individual domestic standard mamushi antivenoms have been used for national quality control (potency testing) of mamushi antivenom products in these countries, because of the lack of an international standard material authorized by the World Health Orga...
متن کاملNeonate-to-adult transition of snake venomics in the short-tailed pit viper, Gloydius brevicaudus.
UNLABELLED Snake venoms undergo ontogenetic shifts in biochemical and pharmacological activities. This may be related to variation in venom components associated with the ontogenetic shift in diet. We used the short-tailed pit viper Gloydius brevicaudus that displays ontogenetic shifts in diet to examine whether the species displays a neonate-to-adult transition of snake venomics. Venoms from n...
متن کاملEvolution of reptilian viviparity: a test of the maternal manipulation hypothesis in a temperate snake, Gloydius brevicaudus (Viperidae).
We kept 48 gravid short-tailed pit vipers (Gloydius brevicaudus) under four laboratory thermal conditions during gestation and collected 10 females from the field soon before they gave birth to test whether Shine's (1995) maternal manipulation hypothesis applies to temperate reptiles. Females thermoregulated more precisely but did not shift their selected body temperatures during pregnancy, wit...
متن کاملProgress and improvement of the manufacturing process of snake antivenom
Antivenoms have been used successfully for more than a century and up to now constitute the only effective treatment for snakebites .The production of antivenin started long time ago when the calmette was prepared the antivenom in 1894.The method currently used to prepare antivenom by most of the manufacturers are originated from the method of Pope which was develop in 1938. Several new approac...
متن کاملProteomic and biochemical analyses of short-tailed pit viper (Gloydius brevicaudus) venom: age-related variation and composition-activity correlation.
UNLABELLED We conducted an in-depth analysis of the proteomic and biochemical profiles of the venom of neonate and adult short-tailed pit vipers (Gloydius brevicaudus). Identified proteins were assigned to a few main toxin families. Disintegrin, phospholipase A2 (PLA2), serine proteinase, cysteine-rich secretory protein, C-type lectin-like protein, l-amino acid oxidase and snake venom metallopr...
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ژورنال
عنوان ژورنال: Toxicological Research
سال: 2020
ISSN: 1976-8257,2234-2753
DOI: 10.1007/s43188-020-00047-0